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El sarampión en pacientes sospechosos de tener fiebre manchada de las Montañas Rocosas
JAMA
|August 22, 1980
Resumen
Se detectaron aumentos en el título de anticuerpos contra el sarampión en individuos inicialmente sospechosos de tener fiebre manchada de las Montañas Rocosas. El sarampión debe considerarse en adolescentes y adultos jóvenes con enfermedades de erupción febril no diagnosticadas.
Área de la Ciencia:
- Enfermedades infecciosas Enfermedades infecciosas.
- Inmunología Inmunología.
- Epidemiología La epidemiología.
Sus antecedentes:
- La fiebre manchada de las Montañas Rocosas (RMSF) es una enfermedad grave transmitida por garrapatas.
- El sarampión es una enfermedad viral altamente contagiosa caracterizada por fiebre y sarpullido.
- El diagnóstico diferencial para las enfermedades de erupción febril puede ser desafiante.
Objetivo del estudio:
- Para investigar el aumento inesperado del título de anticuerpos contra el sarampión en pacientes inicialmente probados para RMSF.
- Para resaltar la importancia de considerar el sarampión en la demografía de pacientes específicos que se presentan con erupción febril.
Principales métodos:
- Pruebas serológicas de sueros emparejados de pacientes con sospecha de RMSF.
- Análisis del aumento del título diagnóstico para los anticuerpos contra el sarampión.
Principales resultados:
- Seis de 46 (13%) individuos inicialmente serológicamente negativos para RMSF mostraron aumentos en el título diagnóstico de anticuerpos contra el sarampión.
- El sarampión atípico o típico es cada vez más frecuente en adolescentes y adultos jóvenes.
Conclusiones:
- El sarampión debe incluirse en el diagnóstico diferencial para adolescentes y adultos jóvenes que presentan enfermedades de erupción febril no diagnosticadas, especialmente cuando se sospecha inicialmente de RMSF pero se descarta.
- La seroconversión inesperada del sarampión puede ocurrir en pacientes con otras enfermedades febriles sospechosas.
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