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Updated: Aug 9, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

Atenuación inducida por la morfina de la tolerancia a la morfina

S Siegel, R E Hinson, M D Krank

    Science (New York, N.Y.)
    |June 26, 1981
    PubMed
    Resumen

    Las señales ambientales que preceden a la administración del fármaco pueden retrasar el desarrollo de la tolerancia a la morfina en ratas. Esto sugiere que las asociaciones aprendidas entre las señales y los períodos libres de drogas pueden contrarrestar la tolerancia a los opiáceos.

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