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Updated: Aug 12, 2026
07:40
A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
Resumen
La presión arterial alta es común en pacientes con accidente cerebrovascular agudo al ingresar. La presión arterial generalmente disminuye dentro de los diez días a medida que la función cerebral se recupera, lo que sugiere una respuesta fisiológica a la isquemia.
Área de la Ciencia:
- Neurología Neurología.
- Cardiología Cardiología.
- Medicina de cuidados críticos Medicina de cuidados críticos.
Sus antecedentes:
- El accidente cerebrovascular agudo se presenta con frecuencia con una presión arterial elevada.
- Comprender el curso natural de la presión arterial después del accidente cerebrovascular es crucial para el manejo.
- La base fisiológica de la hipertensión temprana en el accidente cerebrovascular no está completamente aclarada.
Objetivo del estudio:
- Para investigar la tendencia de la presión arterial en pacientes con accidente cerebrovascular agudo durante los primeros diez días de hospitalización.
- Para determinar si la reducción de la presión arterial se produce espontáneamente sin intervención antihipertensiva.
- Para explorar la relación entre los cambios en la presión arterial y la recuperación de la función cerebral.
Principales métodos:
- Estudio observacional prospectivo de 334 hospitalizaciones consecutivas de ictus agudo.
- Las mediciones de presión arterial en serie se registraron al ingresar y en el décimo día de hospital.
- No se administraron terapias antihipertensivas específicas durante el período de observación.
Principales resultados:
- El 84% de los pacientes exhibieron presión arterial elevada el día de la admisión.
- La presión arterial disminuyó espontáneamente en un promedio de 20 mm Hg sistólica y 10 mm Hg diastólica en diez días.
- Solo un tercio de los casos seguía mostrando presión arterial elevada en el décimo día de hospitalización.
Conclusiones:
- La hipertensión temprana después de un accidente cerebrovascular agudo es probablemente una respuesta fisiológica a la isquemia cerebral.
- La reducción espontánea de la presión arterial se correlaciona con la recuperación neurológica.
- Esta disminución natural sugiere precaución en el tratamiento antihipertensivo inmediato del accidente cerebrovascular agudo.
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