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Métodos para el registro de electrogramas del nodo sinoatrial durante la cirugía cardíaca en el hombre
Circulation
|May 1, 1980
Resumen
Los investigadores registraron con éxito los electrogramas de los nodos sinoatrial (SA) humanos utilizando técnicas extracelulares bipolares y unipolares. Estos métodos ayudan en la localización del nodo SA durante la cirugía y la evaluación funcional en pacientes con enfermedades cardíacas.
Área de la Ciencia:
- Cardiología Cardiología.
- Electrofisiología y electrofisiología.
- Cirugía cardíaca Cirugía cardíaca.
Sus antecedentes:
- Estudios previos demostraron grabaciones de electrogramas extracelulares del nodo sinoatrial (SA) en modelos animales (conejo, perro).
- La electrofisiología del nodo SA humano sigue siendo incompletamente entendida, particularmente en el contexto de las enfermedades cardíacas.
Objetivo del estudio:
- Adaptar y aplicar técnicas de registro extracelular para los electrogramas de los nodos SA humanos.
- Evaluar la eficacia de los métodos de registro bipolar y unipolar para la actividad del nodo SA.
- Evaluar la utilidad clínica potencial de los electrogramas del nodo SA para la localización quirúrgica y la evaluación funcional.
Principales métodos:
- Se registraron electrogramas extracelulares del nodo SA de 23 pacientes de cirugía cardíaca utilizando configuraciones de electrodos bipolares y unipolares.
- Los parámetros de grabación incluyeron polaridad inversa, alta amplificación (100 microV / cm) y filtros de paso bajo (0,15-20 Hz).
- Los tiempos de conducción de SA se midieron en varias longitudes de ciclo sinusal.
Principales resultados:
- Los electrogramas nodulares SA humanos se registraron con éxito en pacientes 8/12 (bipolar) y pacientes 9/11 (unipolar).
- Ambos métodos mostraron tasas de éxito y calidad de grabación comparables, con la técnica unipolar ofreciendo una localización superior del nodo SA.
- Los electrogramas registrados exhibieron pendientes diastólicas y ascendentes, similares a los modelos animales, que preceden a la onda P en el ECG.
Conclusiones:
- La grabación extracelular de los electrogramas nódulos SA humanos es factible utilizando técnicas animales adaptadas.
- Estos métodos pueden ayudar en la localización precisa del nodo SA durante la cirugía a corazón abierto.
- Las técnicas proporcionan una base para evaluar la función del nodo SA en diversas afecciones cardíacas.
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