Una proteína del dominio WD que está asociada y fosforilada por el receptor TGF-beta tipo II

R H Chen1, P J Miettinen, E M Maruoka

  • 1Department of Growth and Development, University of California at San Francisco 94143-0640, USA.

Nature
|October 12, 1995
PubMed
Resumen

Los investigadores descubrieron TRIP-1, una proteína que se une al receptor del factor de crecimiento transformador tipo II-beta (TGF-beta). Esta interacción, crucial para la señalización de TGF-beta, se conserva en todos los eucariotas, lo que sugiere un papel biológico fundamental.

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