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Pedigree Analysis01:35

Pedigree Analysis

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Karyotyping01:17

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Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
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Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
Position-effect Variegation02:32

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...

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Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

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Retention of glycoprotein Ib/IX receptors on external surfaces of thrombin-activated platelets in suspension.

Blood·1995
Same author

A novel hereditary macrothrombocytopenia.

Journal of pediatric hematology/oncology·1995
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A gene causing Hermansky-Pudlak syndrome in a Puerto Rican population maps to chromosome 10q2.

American journal of human genetics·1995
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Dynamic redistribution of glycoprotein Ib/IX on surface-activated platelets. A second look.

The American journal of pathology·1995
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Redistribution of GPIb/IX and GPIIb/IIIa during spreading of discoid platelets.

British journal of haematology·1995
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Talin does not associate exclusively with alpha 2b beta 3 integrin in activated human platelets.

The Journal of laboratory and clinical medicine·1995

Video Experimental Relacionado

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The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging
12:15

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

Published on: October 3, 2017

Mapas del genoma. mapas del genoma. VI. El tiempo. Caenorhabditis elegans. también conocido como caenorhabditis. El

M Chalfie1, S Eddy, M O Hengartner

  • 1Columbia University, New York, NY, USA.

Science (New York, N.Y.)
|October 20, 1995
PubMed
Resumen

No abstract available in PubMed .

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