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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Nuevos factores de riesgo ocupacional para la insuficiencia renal crónica
G D Nuyts1, E Van Vlem, J Thys
1Department of Nephrology-Hypertension, University Hospital Antwerp, Belgium.
Lancet (London, England)
|July 1, 1995
Resumen
Las exposiciones profesionales a metales como el plomo, el mercurio y el estaño, así como los humos y el polvo de soldadura, aumentan significativamente el riesgo de insuficiencia renal crónica (IFC). Se necesita más investigación sobre el polvo de los granos y los vínculos ocupacionales con la nefropatía diabética.
Área de la Ciencia:
- Salud ocupacional y salud en el trabajo.
- Nefrología Nefrología.
- Epidemiología La epidemiología.
Sus antecedentes:
- La insuficiencia renal crónica (IFC) puede estar relacionada con los contaminantes profesionales.
- Los estudios anteriores tenían un alcance limitado y se centraban en diagnósticos específicos o efectos transitorios.
Objetivo del estudio:
- Investigar la asociación entre las exposiciones ocupacionales y la insuficiencia renal crónica de todos los tipos.
- Identificar factores de riesgo ocupacional específicos que contribuyen al desarrollo de CRF.
Principales métodos:
- Un estudio de caso-control que comparó 272 individuos con FRC con 272 controles emparejados.
- Los antecedentes laborales fueron evaluados de forma independiente por higienistas industriales para el grado y la frecuencia de exposición.
Principales resultados:
- Se encontraron aumentos significativos del riesgo de CRF para las exposiciones a plomo, cobre, cromo, estaño, mercurio, humos de soldadura, compuestos de silicio, polvo de granos e hidrocarburos oxigenados.
- Se observaron altas frecuencias de exposiciones ocupacionales en pacientes con nefropatía diabética.
Conclusiones:
- Este estudio confirma los factores de riesgo ocupacional conocidos para la FCR e identifica nuevos contribuyentes potenciales.
- Las funciones del polvo de granos y las exposiciones profesionales en la nefropatía diabética merecen una investigación adicional.
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