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Updated: Aug 2, 2026
07:42
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
Resumen
Un umbral de 10.000 colonias no es confiable para el diagnóstico de candidiasis renal. Un mayor recuento de Candida en la orina puede indicar una infección, lo que justifica una investigación adicional.
Área de la Ciencia:
- La micología de la micología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Microbiología Clínica y Microbiología Clínica.
Sus antecedentes:
- El umbral de 100.000 unidades formadoras de colonias (UFC) se utiliza a menudo para el diagnóstico de la candidiasis renal.
- Este umbral no ha sido rigurosamente evaluado para su exactitud.
Objetivo del estudio:
- Para determinar la incidencia de candiduria y el recuento de colonias de Candida en pacientes sin síntomas de candidiasis.
- Para comparar estos recuentos con los de pacientes con candidiasis renal histológicamente confirmada.
Principales métodos:
- Estudio prospectivo que analizó 1.004 muestras de orina de pacientes sin signos de candidiasis.
- Comparación del recuento de colonias de Candida entre individuos asintomáticos y casos confirmados de candidiasis renal.
Principales resultados:
- La incidencia de candiduria osciló entre el 4% en los hombres y el 39% en las niñas en terapia con antibióticos.
- El recuento medio de colonias en pacientes asintomáticos fue de 1.292 +/- 1.500 UFC/mL.
- El recuento promedio de colonias en casos confirmados de candidiasis renal fue de 23.750 +/- 12.311 UFC/mL.
- La diferencia en el recuento entre casos confirmados y no confirmados fue estadísticamente significativa.
Conclusiones:
- El umbral de 10.000 UFC/mL es un indicador más apropiado para la candidiasis renal potencial.
- Los recuentos de Candida en la orina superiores a 10.000 UFC/mL requieren una investigación de diagnóstico adicional.
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