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Updated: Jul 31, 2026

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
10:07

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Published on: January 27, 2013

Estimulación de los canales de potasio por péptidos natriuréticos a través de la desfosforilación dependiente del

R E White1, A B Lee, A D Shcherbatko

  • 1Laboratory of Cellular and Molecular Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.

Nature
|January 21, 1993
PubMed
Resumen

Los péptidos natriuréticos influyen en la liberación de hormonas a través del monofosfato cíclico de guanosina (cGMP). Este estudio revela que el péptido natriurético auricular estimula los canales BK en las células pituitarias, mediados por la proteína quinasa dependiente de cGMP y la desfosforilación de proteínas.

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