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Interleucina-7: un cofactor para la reorganización V(D) J del gen beta del receptor de células T

K Muegge1, M P Vila, S K Durum

  • 1Biological Carcinogenesis and Development Program, Program Resources Inc./Dyncorp, National Cancer Institute-Frederick Cancer Research and Development Center, MD 21702.

Science (New York, N.Y.)
|July 2, 1993
PubMed
Resumen

La interleucina-7 (IL-7) se identifica como una señal clave que impulsa la reorganización del gen del receptor de células T en el desarrollo de las células T. Esta citoquina sostiene la expresión de los genes RAG esenciales para la recombinación V(D) J en los timocitos embrionarios.

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