Video Experimental Relacionado

Updated: Aug 11, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

Catalización eficiente de las reorganizaciones de enlaces disulfuro por isomerasa disulfuro de proteínas

J S Weissman1, P S Kim

  • 1Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Department of Physics, Cambridge, Massachusetts 02142.

Nature
|September 9, 1993
PubMed
Resumen

La proteína disulfuro isomerasa (PDI) acelera significativamente el plegamiento oxidativo de los intermediarios complejos de proteínas. Esta enzima clave facilita la formación de enlaces disulfuro en estructuras atrapadas cinéticamente, mejorando la eficiencia de plegamiento de las proteínas.

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