Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

What is the Cell Cycle?01:04

What is the Cell Cycle?

218.7K
The cell cycle refers to the sequence of events occurring throughout a typical cell’s life. In eukaryotic cells, the somatic cell cycle has two stages: interphase and the mitotic phase. During interphase, the cell grows, performs its basic metabolic functions, copies its DNA, and prepares for mitotic cell division. Then, during mitosis and cytokinesis, the cell divides its nuclear and cytoplasmic materials, respectively. This generates two daughter cells that are identical to the original...
218.7K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

4.7K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
4.7K
Mitogens and the Cell Cycle02:38

Mitogens and the Cell Cycle

7.2K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
7.2K
Molecular Factors Affecting Cell Division01:27

Molecular Factors Affecting Cell Division

3.5K
Several external and internal factors influence the initiation and inhibition of cell division. For instance, the death of nearby cells or the release of human growth hormone (hGH) promotes cell division. In contrast, lack of hGH or crowding of cells can inhibit cell division.
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
3.5K
The Cell Cycle Control System01:28

The Cell Cycle Control System

4.4K
The cell cycle regulation directs how a cell proceeds from one phase to the next and begins mitosis. The cell cycle control system includes intracellular regulatory molecules and external triggers. They provide "stop" or "advance" signals and operate at specific cell cycle stages termed checkpoints to ensure that a particular process is completed before the cell advances to the next phase.
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
4.4K
The Cell Cycle Control System02:11

The Cell Cycle Control System

12.9K
The cell cycle is an organized set of events that leads the cell to divide into two daughter cells, each containing chromosomes identical to the parent cell. It is the cell cycle that leads to the formation of an entire organism from a single-cell zygote. Besides, cell division also functions in the renewal or repair of tissues in adult multicellular eukaryotes. For example, in the bone marrow, the stem cells divide to form new blood cells. Although essential for several functions, cell...
12.9K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Final analysis of the ALTTO trial: adjuvant trastuzumab in sequence or in combination with lapatinib in patients with HER2-positive early breast cancer [BIG 2-06/NCCTG N063D (Alliance)].

ESMO open·2024
Same author

Patterns of African and Asian admixture in the Afrikaner population of South Africa.

BMC biology·2020
Same author

Surgical repair <i>versus</i> conservative treatment and subacromial decompression for the treatment of rotator cuff tears: a meta-analysis of randomized trials.

The bone & joint journal·2019
Same author

Cucurbit yellow stunting disorder virus (Genus Crinivirus) Associated with the Yellowing Disease of Cucurbit Crops in Portugal.

Plant disease·2019
Same author

Silk flow-diverter stent for the treatment of complex intracranial aneurysms: A one-year follow-up multicenter study.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2018
Same author

Pulmonary hypertension: Real-world data from a Portuguese expert referral centre.

Pulmonology·2018

Video Experimental Relacionado

Updated: Oct 28, 2025

Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves
08:31

Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves

Published on: December 2, 2016

11.1K

La longitud celular, el crecimiento celular y la división celular.

W D Donachie, K J Begg, M Vicente

    Nature
    |November 25, 1976
    PubMed
    Resumen
    Este resumen es generado por máquina.

    Las células bacterianas de Escherichia coli (E. coli) se duplican en longitud antes de dividirse. Esta longitud crítica de la célula desencadena un crecimiento y división más rápidos, independientemente de la finalización de la replicación del ADN.

    Más Videos Relacionados

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines
    12:35

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines

    Published on: September 3, 2016

    19.7K
    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry
    11:23

    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry

    Published on: May 22, 2012

    21.2K

    Videos de Experimentos Relacionados

    Last Updated: Oct 28, 2025

    Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves
    08:31

    Kinematic Analysis of Cell Division and Expansion: Quantifying the Cellular Basis of Growth and Sampling Developmental Zones in Zea mays Leaves

    Published on: December 2, 2016

    11.1K
    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines
    12:35

    Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines

    Published on: September 3, 2016

    19.7K
    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry
    11:23

    Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry

    Published on: May 22, 2012

    21.2K

    Área de la Ciencia:

    • Microbiología Microbiología.
    • Biología celular Biología celular.
    • Fisiología bacteriana fisiología bacteriana.

    Sus antecedentes:

    • Comprender la división celular bacteriana es crucial para controlar el crecimiento microbiano.
    • Escherichia coli sirve como un organismo modelo para el estudio de los procesos fundamentales de la biología celular.
    • La regulación del tamaño celular tiene un impacto en la proliferación bacteriana y la viabilidad.

    Objetivo del estudio:

    • Para investigar la longitud crítica de la célula que desencadena la división en E. coli.
    • Para determinar la relación entre la tasa de alargamiento celular, la división celular y la replicación del ADN.
    • Para identificar el mecanismo de señalización que inicia el proceso de división celular.

    Principales métodos:

    • Técnicas de microscopía para monitorear el alargamiento y la división celular.
    • Análisis de las condiciones de crecimiento para evaluar la consistencia de longitud crítica.
    • Análisis de correlación entre la longitud celular y el estado de replicación del ADN.

    Principales resultados:

    • Las células de E. coli alcanzan una longitud crítica, aproximadamente el doble de la longitud mínima, bajo diversas condiciones de crecimiento.
    • En esta longitud crítica, las células aumentan abruptamente su tasa de alargamiento.
    • La división celular ocurre aproximadamente 20 minutos después de alcanzar la longitud crítica.
    • La replicación del cromosoma termina alrededor de la longitud crítica de la célula, pero no inicia la señal de división.

    Conclusiones:

    • La longitud celular, no el estado de replicación del ADN, es el desencadenante principal para la transición a la rápida elongación y división en E. coli.
    • Un punto de control de tamaño crítico rige la progresión del ciclo celular bacteriano.
    • Este mecanismo dependiente de la longitud asegura el tamaño adecuado de la célula antes de la división en diferentes entornos.