Video Experimental Relacionado
Updated: Aug 13, 2026
08:57
Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
Published on: October 5, 2017
¿Nos atrevemos a contar el costo de la quimioterapia contra el cáncer?
Lancet (London, England)
|September 2, 1978
Resumen
El costo de los medicamentos citotóxicos de quimioterapia aumentó significativamente entre 1972 y 1976, a pesar de la incidencia estable de cáncer. Estos costosos tratamientos contra el cáncer no son una alternativa barata a las terapias tradicionales.
Área de la Ciencia:
- Oncología Oncología.
- Economía de la salud Economía de la salud
- Farmacoeconomía La farmacoeconomía es la economía de las drogas.
Sus antecedentes:
- La incidencia del cáncer y el número de pacientes se mantuvieron estables en el Reino Unido entre 1972-1976.
- La proporción del presupuesto de medicamentos de un gran hospital asignado a medicamentos citotóxicos aumentó sustancialmente durante este período.
Objetivo del estudio:
- Para analizar el aumento de los costos asociados con el uso de fármacos citotóxicos en el tratamiento del cáncer.
- Evaluar la viabilidad económica de la quimioterapia citotóxica en comparación con la cirugía y la radioterapia.
Principales métodos:
- Análisis retrospectivo de los presupuestos de medicamentos hospitalarios y los datos de uso de drogas.
- Comparación de los costos de los medicamentos, la incidencia de los pacientes y las modalidades de tratamiento.
Principales resultados:
- El uso de fármacos citotóxicos aumentó del 5,1% al 14% del presupuesto total de medicamentos hospitalarios.
- El aumento de los costos fue impulsado por un mayor uso y precios unitarios de cuatro medicamentos específicos y caros.
- A pesar del aumento de los costos, la quimioterapia citotóxica no es una alternativa rentable a la cirugía y la radioterapia.
Conclusiones:
- El uso de costosos fármacos citotóxicos debe limitarse a los intentos curativos o ensayos clínicos.
- Se necesita más investigación para optimizar el uso de medicamentos citotóxicos menos costosos para la atención paliativa en cáncer avanzado.
Más Videos Relacionados
15:04Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
05:36Quantifiable and Inexpensive Cell-Free Fluorescent Method to Confirm the Ability of Novel Compounds to Chelate Iron
Published on: February 23, 2024
Videos de Conceptos Relacionados
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:56Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
02:50Combination Therapies and Personalized Medicine
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:56Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
01:21Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...