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Inervación eferente simpática y vagal del ventrículo derecho canino
1Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202-4800.
Circulation
|September 1, 1994
Resumen
La investigación de las vías de inervación del ventrículo derecho (VR) reveló las ubicaciones del nervio simpático y vagal. Las fibras simpáticas son principalmente superficiales, mientras que las fibras vagales son superficiales y profundas, con algunas diferencias en el tracto de salida de RV.
Área de la Ciencia:
- Fisiología cardiovascular fisiología cardiovascular.
- La innervación cardíaca es una inervación cardíaca.
- El sistema nervioso autónomo.
Sus antecedentes:
- La pared del ventrículo derecho (VR) está implicada en varios estados de enfermedad.
- La comprensión de las vías de inervación eferente simpática y vaga a la RV es crucial.
Objetivo del estudio:
- Para investigar las vías funcionales de inervación eferente simpática y vaga al ventrículo derecho.
Principales métodos:
- Ablación de fenol y radiofrecuencia endocárdica aplicada a la pared anterolateral del RV y al tracto de salida.
- El acortamiento / alargamiento del período refractario efectivo evaluado (EPR) durante la estimulación simpática y vagal.
Principales resultados:
- Los axones simpáticos eferentes a la RV se encuentran principalmente en el subepicardio superficial.
- Los sitios de inervación simpática varían según la ubicación (lateral vs. medial), con algunas fibras intramurales en el tracto de salida.
- Las fibras vagales eferentes se encuentran en la superficie de la RV cerca de la ranura AV, penetrando intramuralmente, con algunas originadas cerca de la LAD y otras intramurales en el tracto de salida.
Conclusiones:
- La inervación vagal eferente y la inervación simpática de la RV comparten similitudes con el ventrículo izquierdo.
- Una distinción clave es la presencia de fibras simpáticas subendocárdicas en el tracto de salida de RV, a diferencia del ventrículo izquierdo.
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