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La profilaxis de la aspirina en la migraña
Lancet (London, England)
|December 2, 1978
Resumen
La profilaxis con aspirina redujo significativamente la frecuencia de la migraña en más del 50% en la mayoría de los pacientes. Este estudio piloto sugiere que la aspirina es una opción efectiva para la prevención de la migraña.
Área de la Ciencia:
- Neurología Neurología.
- Farmacología Farmacología.
Sus antecedentes:
- La migraña es un trastorno neurológico común.
- Se necesitan tratamientos profilácticos efectivos.
Objetivo del estudio:
- Para evaluar la eficacia de la aspirina para la profilaxis de la migraña.
Principales métodos:
- Estudio prospectivo, doble ciego, controlado con placebo.
- Se incluyeron 12 pacientes con migraña.
Principales resultados:
- La aspirina redujo la frecuencia del dolor de cabeza en >50% en 9/12 pacientes.
- La respuesta no se correlacionó con la demografía del paciente o la ultrastructura plaquetaria.
- La respuesta a la aspirina puede estar relacionada con un aumento de la agregación plaquetaria.
Conclusiones:
- La aspirina parece ser eficaz para la profilaxis de la migraña.
- Se justifica una mayor investigación sobre el mecanismo.
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