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Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
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El wee1 humano mantiene el tiempo mitótico protegiendo el núcleo de la cinasa Cdc2 activada citoplasmáticamente

R Heald1, M McLoughlin, F McKeon

  • 1Department of Cellular and Molecular Physiology, Harvard Medical School, Boston, Massachusetts 02115.

Cell
|August 13, 1993
PubMed
Resumen

La wee1 quinasa humana protege el núcleo de la quinasa cdc2 activada citoplasmáticamente, asegurando la finalización de la replicación del ADN antes de la mitosis. Esto evita la entrada mitótica catastrófica, coordinando la progresión del ciclo celular.

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