Video Experimental Relacionado

Updated: Feb 10, 2026

Phase Transitions and Effect of Intermolecular Forces

Phase Transitions and Effect of Intermolecular Forces

Codificación de la información olfativa: topografía de la expresión de los receptores olfativos en el epitelio

J Ngai¹, A Chess, M M Dowling

¹Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, New York 10032.

|March 12, 1993

Resumen

Las neuronas olfativas individuales expresan receptores olfativos distintos, lo que permite al cerebro identificar olores específicos. Este hallazgo apoya un modelo en el que las neuronas específicas del receptor se proyectan a glomérulos del bulbo olfativo común.

Área de la Ciencia:

La neurociencia es la neurociencia.
Investigación del sistema olfativo en el sistema olfativo.
Biología sensorial La biología sensorial.

Sus antecedentes:

La discriminación del olor se basa en la identificación de los receptores de olor activados.
Las neuronas olfativas expresan un subconjunto del repertorio total de receptores olfativos.

Objetivo del estudio:

Investigar si las neuronas olfativas individuales expresan complementos únicos de los receptores olfativos.
Para determinar si las neuronas olfativas son funcionalmente distintas basadas en la expresión del receptor.

Principales métodos:

Se realizaron experimentos de hibridación in situ.
Análisis de la expresión de los receptores olfativos en las neuronas olfativas individuales.

Principales resultados:

Las neuronas olfativas individuales expresan diferentes conjuntos de receptores olfativos, lo que confirma la distinción funcional.
Las neuronas que expresan receptores específicos se distribuyen al azar en el epitelio olfativo.

Conclusiones:

Los hallazgos apoyan un modelo de procesamiento olfativo donde neuronas específicas que expresan receptores se proyectan a glomérulos comunes en el bulbo olfativo.
Se puede utilizar un mapa topográfico para determinar la calidad del estímulo olfativo en función de los patrones de activación neuronal.

Más Videos Relacionados

Transition Metals: Electron Configurations and Properties

Transition Metals: Electron Configurations and Properties

Cooperative Allosteric Transitions: Concerted & Sequential Model

Cooperative Allosteric Transitions: Concerted & Sequential Model

Videos de Conceptos Relacionados

Phase Transitions

Phase Transitions

Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...

Properties of Transition Metals

Properties of Transition Metals

Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.

Cooperative Allosteric Transitions

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...

Phase Transitions: Vaporization and Condensation

Phase Transitions: Vaporization and Condensation

The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...

Phase Transitions: Sublimation and Deposition

Phase Transitions: Sublimation and Deposition

Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...

Phase Transitions: Melting and Freezing

Phase Transitions: Melting and Freezing

Heating a crystalline solid increases the average energy of its atoms, molecules, or ions, and the solid gets hotter. At some point, the added energy becomes large enough to partially overcome the forces holding the molecules or ions of the solid in their fixed positions, and the solid begins the process of transitioning to the liquid state or melting. At this point, the temperature of the solid stops rising, despite the continual input of heat, and it remains constant until all of the solid is...