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Updated: Jun 22, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

Pref-1, una proteína que contiene repeticiones similares al FEA, inhibe la diferenciación de los adipocitos

C M Smas1, H S Sul

  • 1Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115.

Cell
|May 21, 1993
PubMed
Resumen

El factor 1 de los preadipocitos (Pref-1) es una nueva proteína que inhibe la diferenciación de las células grasas. El bloqueo de su regulación descendente en los preadipocitos reduce drásticamente la diferenciación adiposa, identificando a Pref-1 como un regulador negativo clave.

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