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Preparation of Horizontal Slices of Adult Mouse Retina for Electrophysiological Studies
Published on: January 27, 2017
Células horizontales de la retina de los primates: especificidad de cono sin oponencia espectral
D M Dacey1, B B Lee, D K Stafford
1Department of Biological Structure, University of Washington, Seattle 98195-7420, USA.
Resumen
Las células horizontales en la retina de los primates no exhiben oponencia espectral. Este hallazgo sugiere que la base neuronal para la visión del color es la visión del color.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- Visión Visión Ciencia Ciencia.
- Fisiología de la retina Fisiología de la retina
Sus antecedentes:
- La visión de color humana se basa en el procesamiento neuronal de la retina.
- Las células ganglionares de la retina muestran oponencia espectral, respondiendo a diferentes longitudes de onda con excitación o inhibición.
Objetivo del estudio:
- Para investigar la hipótesis de que las células horizontales forman circuitos oponentes con fotorreceptores de cono.
- Para determinar si las células horizontales son el origen de la oponencia espectral en los primates.
Principales métodos:
- Caracterización fisiológica y anatómica de las conexiones de los conos con los mosaicos celulares horizontales en monos macacos.
- Análisis de las respuestas celulares horizontales a diferentes tipos de conos (conos L, M y S).
Principales resultados:
- Las celdas horizontales H1 recibieron información exclusivamente de los conos L y M.
- Las celdas horizontales H2 recibieron una fuerte entrada de los conos S y una entrada más débil de los conos L y M.
- Todas las entradas de cono a las celdas horizontales eran del mismo signo, y ni las celdas H1 ni H2 mostraron oposición.
Conclusiones:
- Las células horizontales en primates, incluidos los humanos, no exhiben oponencia espectral.
- El circuito de las celdas horizontales no apoya la hipótesis de que son el lugar de las transformaciones de color del oponente.
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