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Especificación de linajes celulares pituitarios por el gen LIM homeobox Lhx3

H Z Sheng1, A B Zhadanov, B Mosinger

  • 1Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|May 17, 1996
PubMed
Resumen

El gen homeobox LIM Lhx3 es crucial para el desarrollo de la hipófisis en ratones. Su ausencia impide la diferenciación de la bolsa de Rathke, lo que afecta a la mayoría de los linajes celulares de la hipófisis, excepto a los corticotróficos.

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