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La acetilhidrolasa cerebral que inactiva el factor de activación plaquetaria es un trímero similar a la proteína G

Y S Ho1, L Swenson, U Derewenda

  • 1Department of Molecular Physiology and Biological Physics, University of Virginia Health Sciences Center, Charlottesville 22906-0011, USA.

Nature
|January 2, 1997
PubMed
Resumen

El factor de activación plaquetaria (PAF) es crucial en la señalización celular. Los investigadores determinaron la estructura cristalina de una enzima clave, la subunidad alfa1 de acetilhidrolasa PAF, revelando su estructura similar a la proteína G y su sitio activo.

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