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Updated: Sep 10, 2026

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis
12:29

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis

Published on: April 16, 2018

La inhibición del oligonucleótido antisense de la expresión de la subunidad del receptor PDGFR-beta dirige la

M G Sirois1, M Simons, E R Edelman

  • 1Harvard-MIT Division of Health Sciences and Technology, Cambridge, Brigham and Women's Hospital (E.R.E.), Boston, Mass, USA. mgsirois@mit.edu

Circulation
|February 4, 1997
PubMed
Resumen

Los oligonucleótidos antisense dirigidos al receptor beta del factor de crecimiento derivado de las plaquetas (PDGFR-beta) redujeron significativamente la formación de neointimales después de una lesión vascular. La supresión de la expresión de PDGFR-beta o su activación por PDGF-BB es una estrategia terapéutica potencial para la enfermedad vascular.

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