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1Department of Medical Microbiology, University Medical School, Edinburgh, UK.
Lancet (London, England)
|March 1, 1997
Resumen
La encefalopatía espongiforme bovina (BSE), o "enfermedad de las vacas locas", surgió en 1986, causando muertes significativas de ganado y infecciones de rebaños en el Reino Unido. Este artículo resume los desarrollos recientes en la comprensión de este trastorno neurológico en el ganado.
Área de la Ciencia:
- Neurología Veterinaria Neurología Veterinaria.
- Epidemiología La epidemiología.
- Patología Patología Patología.
Sus antecedentes:
- La encefalopatía espongiforme bovina (BSE), conocida como "enfermedad de las vacas locas", fue identificada en 1986.
- Para enero de 1997, más de 165.000 muertes de ganado en el Reino Unido se atribuyeron a la EEB, que afectó a aproximadamente 34.000 rebaños.
- Los signos clínicos en el ganado afectado incluyen alteración de la postura y el temperamento, aprehensión y pérdida de coordinación.
Objetivo del estudio:
- Revisar la epidemiología y la presentación clínica de la encefalopatía espongiforme bovina (ESB).
- Para resaltar las similitudes neuropatológicas entre la EEB en el ganado y la tembladera en las ovejas.
- Para resumir los recientes desarrollos relacionados con la EEB, sobre la base de revisiones anteriores.
Principales métodos:
- Revisión de la literatura de los datos existentes y hechos publicados sobre la EEB.
- Análisis comparativo de los hallazgos neuropatológicos en EEB y scrapie.
- Síntesis de los últimos desarrollos en el campo.
Principales resultados:
- La EEB es una enfermedad significativa que afecta a las poblaciones de ganado bovino, particularmente en el Reino Unido.
- El examen neuropatológico revela cambios espongiformes en el cerebro posterior, similares a la tembladera.
- La enfermedad ha sido ampliamente documentada en la literatura científica.
Conclusiones:
- La encefalopatía espongiforme bovina presenta síntomas neurológicos y conductuales distintos en el ganado.
- Los cambios espongiformes observados en el cerebro son una característica de diagnóstico clave.
- La investigación y las revisiones en curso son cruciales para comprender y manejar los brotes de EEB.
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