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Nueva variante de la enfermedad de Creutzfeldt-Jakob: características psiquiátricas
M Zeidler1, E C Johnstone, R W Bamber
1National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, UK.
Lancet (London, England)
|October 7, 1997
Resumen
La nueva variante de la enfermedad de Creutzfeldt-Jakob (nvCJD) se presenta constantemente con síntomas psiquiátricos tempranos, a menudo imitando la depresión. Distinguir nvCJD requiere la vigilancia de los signos neurológicos junto con las características psiquiátricas.
Área de la Ciencia:
- Neurología Neurología.
- La psiquiatría es la psiquiatría.
Sus antecedentes:
- Una nueva variante de la enfermedad de Creutzfeldt-Jakob (nvCJD) surgió en 1996.
- nvLos casos de ECCJ se presentan predominantemente con síntomas psiquiátricos.
Objetivo del estudio:
- Para detallar las características psiquiátricas de los casos tempranos de nvCJD.
- Evaluar la utilidad diagnóstica de los síntomas psiquiátricos en la ECJ.
Principales métodos:
- Revisión de las notas de caso y entrevistas de familiares para 14 casos de la CVJD.
- Evaluación psiquiátrica de 13 casos.
Principales resultados:
- Todos los 14 casos exhibieron rasgos psiquiátricos tempranos; el primer síntoma de nueve fue psiquiátrico.
- La mayoría de los diagnósticos psiquiátricos fueron depresión o depresión secundaria a una enfermedad orgánica.
- Los síntomas psicóticos y las alucinaciones ocurrieron en algunos casos, con signos neurológicos que se desarrollaron más tarde.
Conclusiones:
- Los síntomas psiquiátricos son un indicador temprano consistente de la enfermedad de la médula ósea sin cráneo.
- Distinguir nvCJD de los trastornos psiquiátricos comunes es un desafío basado solo en los síntomas psiquiátricos.
- El desarrollo de déficits neurológicos es crucial para el diagnóstico de la ECJ.
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