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Updated: May 5, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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Published on: August 3, 2018

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La trombospondina-1 es uno de los principales activadores del TGF-beta1 in vivo

S E Crawford1, V Stellmach, J E Murphy-Ullrich

  • 1Robert H. Lurie Cancer Center, Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

Cell
|July 10, 1998
PubMed
Resumen

La trombospondina-1 (TSP-1) activa significativamente el factor de crecimiento transformador-beta1 (TGF-beta1) in vivo. El tratamiento con péptido TSP-1 revirtió las anomalías pulmonares y de páncreas inducidas por la deficiencia de TGF-beta1 en ratones.

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