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Estructura cristalina de los tres primeros dominios del receptor del factor de crecimiento similar a la insulina tipo

T P Garrett1, N M McKern, M Lou

  • 1Biomolecular Research Institute, Parkville, Victoria, Australia. tom.barrett@bioresi.com.au

Nature
|August 5, 1998
PubMed
Resumen

Determinamos la estructura de los dominios clave en el receptor del factor de crecimiento similar a la insulina tipo 1 (IGF-1R). Esto revela cómo IGF-1R y los receptores de insulina relacionados (IR) pueden unirse a sus ligandos.

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