Identificación de dos mecanismos distintos de fagocitosis controlados por las diferentes Rho GTPasas

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"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy (TIRFM)
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Published on: August 26, 2016

E Caron1, A Hall

  • 1Medical Research Council Laboratory for Molecular Cell Biology, Cancer Research Campaign Oncogene and Signal Transduction Group, and Department of Biochemistry, University College London, Gower Street, London WC1E 6BT, UK.

Science (New York, N.Y.)
|November 30, 1998
PubMed
Resumen

Los receptores de complemento e inmunoglobulina median la fagocitosis a través de distintas vías de la Rho GTPasa. La captación del receptor de inmunoglobulina desencadena la inflamación, mientras que la captación del receptor del complemento no lo hace, revelando diferencias moleculares en las respuestas de los macrófagos.

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