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Cloruro de benzalconio acuoso y contaminado. Un riesgo innecesario de infección hospitalaria
JAMA
|November 22, 1976
Resumen
Un brote de sepsis en un hospital rural se relacionó con infusiones intravenosas contaminadas y el cloruro de benzalconio antiséptico. Esto pone de relieve el riesgo de infección planteado por ciertos antisépticos, recomendando alternativas más seguras.
Área de la Ciencia:
- Enfermedades infecciosas Enfermedades infecciosas.
- Microbiología Microbiología.
- Epidemiología de los hospitales.
Sus antecedentes:
- La técnica aséptica es crucial para prevenir las infecciones asociadas a la atención médica.
- Las infusiones intravenosas son procedimientos médicos comunes con riesgos inherentes de infección.
- El cloruro de benzalconio es un antiséptico ampliamente utilizado en entornos de atención médica.
Objetivo del estudio:
- Para investigar la causa de un brote inesperado de sepsis en una sala de hospital.
- Para identificar la fuente de la infección por Pseudomonas cepacia en nueve pacientes.
- Evaluar el papel de la técnica aséptica y el uso de antisépticos en el brote.
Principales métodos:
- Revisión retrospectiva del caso de nueve pacientes con sepsis.
- Investigación microbiológica de cultivos de sangre de pacientes.
- Muestreo y análisis de las infusiones intravenosas en uso.
- Análisis del agente antiséptico, el cloruro de benzalconio acuoso.
Principales resultados:
- Nueve pacientes desarrollaron sepsis durante enero y febrero de 1975.
- Pseudomonas cepacia fue identificado como el agente causal.
- Las bacterias se recuperaron del torrente sanguíneo del paciente, las infusiones intravenosas y el cloruro de benzalconio.
Conclusiones:
- Las infusiones intravenosas contaminadas y el cloruro de benzalconio estuvieron implicados en el brote de sepsis.
- El uso de cloruro de benzalconio acuoso presenta un riesgo significativo de infección.
- Se deben seleccionar alternativas antisépticas y desinfectantes más seguras para prevenir futuros brotes.
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