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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Altas tasas de mutación genómica dañina en los homínidos

A Eyre-Walker1, P D Keightley

  • 1Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton, UK. A.C.Eyre-Walker@susx.ac.uk

Nature
|February 9, 1999
PubMed
Resumen

Los seres humanos experimentan una alta tasa de nuevas mutaciones dañinas, con más de 1,6 por genoma por generación que afectan a las secuencias codificantes de proteínas. La selección natural elimina muchos, pero esta tasa de cepas de especies con bajas tasas de reproducción.

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