東南アジア出身の成人のチアミン欠乏症とマラリア
S Krishna1, A M Taylor, W Supanaranond
1Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Lancet (London, England)
|February 24, 1999
まとめ
タイのマラリア患者,特に重症の感染者ではチアミン欠乏が一般的です. この欠乏は,マラリア症例における中枢神経系の合併症を悪化させる可能性があります.
科学分野:
- トロピカル・メディシン (熱帯医学)
- 栄養科学とは,栄養科学である.
- 感染症 感染症は感染症です.
背景:
- シアミン欠乏症 (ベリベリ) は,東南アジアで一般的です.
- 急性チアミン欠乏症の症状は,マラリアの合併症である脳症や乳酸酸化症に似ている可能性があります.
- この研究では,タイの入院マラリア患者におけるチアミン欠乏症の発生率を調査した.
研究 の 目的:
- タイでマラリアで入院した成人のチアミン欠乏症の発生率を決定する.
- マラリアの重症度との関係でチアミン欠乏症の重症度を評価する.
- マラリアにおける中枢神経系の機能障害に対するチアミン欠乏の潜在的貢献を調査する.
主な方法:
- タイのPaholpolpayuhasena病院で実施された前向きな研究 (1992年5月~7月).
- マラリアや熱性疾患の連続した患者と健康な対照群を募集した.
- ティアミン欠乏症 (アルファ > 1.31) を定義するために,赤血球トランケトラーゼ活性化係数 (アルファ) を測定した.
主要な成果:
- ティアミンの欠乏症は,重度のマラリア患者の52%と,合併症のないマラリア患者の19%で検出されました.
- ティアミン欠乏症は,重症および無合併症のマラリア群において,対照群と比較して有意に多く見られた.
- 欠乏症は,脳マラリアの患者でより重症でした.
結論:
- チアミンの欠乏は,タイの入院した成人の急性ファルシパラムマラリアをしばしば複雑にします.
- この欠乏症は,マラリアの重大な感染を患っている患者に特に一般的で重症である.
- チアミンの欠乏は,重度のマラリア症例で観察される中枢神経系の機能障害に寄与する可能性があります.
キーワード:
アジア アジア アジア生物学 生物学 生物学とはケース・コントロール研究 ケース・コントロール研究欠乏性疾患 欠乏性疾患とは発展途上国 開発途上国病気 病気 病気マラリアはマラリアです.マイクロニュートリエント マイクロニュートリエント栄養失調症 栄養失調症について寄生虫による病気生理学 生理学とは研究方法論 研究方法論研究報告書 研究報告書東南アジア 南東アジア勉強 勉強 勉強 勉強 勉強タイ タイ タイ タイ.ビタミン ビタミンさらに関連する動画
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