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Updated: Jul 23, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

核酸内のすべての酸素は,発がん性エチル剤と反応する.

B Singer

    Nature
    |November 25, 1976
    PubMed
    まとめ

    エチルニトロス尿素とエチルニトロスグアニジンは,主に核酸の酸素を改変する. 反応性は,単一鎖のRNA/DNAと二鎖のDNAの間で異なっており,O2-アルキルピリミジンはラビルなグリコシド結合を示しています.

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