関連する実験動画
Updated: Jul 13, 2026
11:10
Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
Published on: November 16, 2011
タンパク質チロシンフォスファタゼ-1B遺伝子が欠けているマウスのインスリン感受性および肥満抵抗性の増加
M Elchebly1, P Payette, E Michaliszyn
1Department of Biochemistry, McGill University, 3655 Drummond Street, Montreal, Quebec, Canada, H3G 1Y6.
Science (New York, N.Y.)
|March 5, 1999
まとめ
タンパク質チロシンフォスファタゼ-1B (PTP-1B) の除去は,マウスのインスリン感受性とグルコース代謝を改善する. PTP-1B欠乏症は,食事による肥満やインスリン抵抗性も予防します.
科学分野:
- バイオケミストリー バイオケミストリー
- メタボリック研究
背景:
- タンパク質チロシンフォスファタゼ-1B (PTP-1B) は,インスリンシグナル伝達を否定的に調節する.
- PTP-1Bの役割を調査することは,代謝障害を理解するために不可欠です.
関連する概念動画
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02:41Lethal Alleles
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Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...