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Updated: Jul 12, 2026

Interview: Protein Folding and Studies of Neurodegenerative Diseases
19:50

Interview: Protein Folding and Studies of Neurodegenerative Diseases

Published on: July 16, 2008

モノメアヒトプリオンタンパク質のネイティブとフィブリロゲン形状の可逆変換

G S Jackson1, L L Hosszu, A Power

  • 1Prion Disease Group, Department of Neurogenetics, Imperial College School of Medicine at St. Mary's, London W2 1NY, UK.

Science (New York, N.Y.)
|March 19, 1999
PubMed
まとめ

研究者らは,再結合ヒトプリオンタンパク質 (PrP) がアルファヘリル構造とベータシート構造の間で変換するための条件を特定しました. このβ-PrP形態は,病気に関連したPrPScを模倣し,プリオン伝播機構の洞察を提供します.

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