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異なった電極構成と2相容量における除細動値に対する二相性ショック期間の影響:脆弱性の上限決定による予測
P N Schauerte1, K Ziegert, M Waldmann
1University of Technology, Department of Cardiology and Cardiovascular Surgery, Aachen, Germany. Patrick-Schauerte@ouhsc.edu
Circulation
|March 23, 1999
まとめ
脆弱性の上限 (ULV) は,除細動値 (DFT) の波形を予測することができます. 低相2容量は,二相ショック期間 (BSD) にかかわらず,DFTを減少させます.
科学分野:
- 心血管の生理学 心血管の生理学
- 電気生理学 電気生理学
- 医療機器工学 医療機器工学とは
背景:
- デフィブリレーションスリーホールド (DFT) は,二相ショック持続時間 (BSD),電極構成,電容量によって影響を受けます.
- 脆弱性の上限 (ULV) は,DFTの推定値として役立つ可能性があります.
研究 の 目的:
- ULVが,DFTが最も低い波形を予測できるかどうかを調べる.
- 豚のULVを使用して,DFT予測に対する異なるリード構成とフェーズ2容量の影響を評価する.
主な方法:
- 18匹の豚の10種類のBSDで,上下プロトコルを用いてDFTとULVを決定した.
- 静脈ペースでT波スキャニングでULVを測定した.
- 2つの電極構成 (AC+SVCとAC) と様々な容量 (150μFと300μF) を利用しました.
主要な成果:
- ULVとDFTは,すべてのプロトコルで有意な線形相関関係 (r=0.78から0.84) を示した.
- 最低のDFTは,AC+SVCでは10ms,ACでは14msで観察されました.
- フェーズ2の電容量を低下させると,DFTが低下し,それを上昇させると,DFTの最小値が上昇した.
結論:
- ULVの決定は,最も低いDFTを持つ波形を予測することができます.
- 最低値のDFTのための最適なBSDは,AC+SVCとACの構成によって異なります.
- 減少したフェーズ2容量は,DFTを低下させるのに有益である.
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