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Updated: Jul 17, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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Aktは,フォークヘッドの転写因子をリン酸化し,抑制することによって細胞生存を促進します

A Brunet1, A Bonni, M J Zigmond

  • 1Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|April 2, 1999
PubMed
まとめ

生存因子は,転写因子FKHRL1.1を調節することによって,細胞死を防ぐ. アクトリン酸化はFKHRL1を細胞質に保ちますが,その欠如は核の侵入とアポトーシスを引き起こす.

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