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Updated: Jul 10, 2026

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis
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Apaf-1とcaspase-9はp53-依存アポトーシスと腫瘍抑制に作用する

M S Soengas1, R M Alarcón, H Yoshida

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Science (New York, N.Y.)
|April 2, 1999
PubMed
まとめ

腫瘍抑制剤p53は,アポトーシスの誘導のためにカスパゼ9とApaf-1に依存しています. p53のようなこれらのタンパク質の喪失は,腫瘍遺伝子の駆動による細胞生存を可能にすることで,癌を促進します.

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