妊娠中のパルボウイルスB19感染のリスク要因
A K Valeur-Jensen1, C B Pedersen, T Westergaard
1Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen.
JAMA
|April 3, 1999
まとめ
妊婦は,特に子供との接触が増えた場合,流行の間,パルボウイルスB19感染のリスクが高い. ほとんどの感染症は,女性の子供との接触から発生し,公衆衛生上の重大な懸念を強調しています.
科学分野:
- エピデミオロジー エピデミオロジー
- ウイルス学 ウイルス学 ウイルス学
- 公衆衛生は公衆衛生である.
背景:
- 妊娠中のパルボウイルスB19感染は胎児死亡と関連しています.
- 妊娠中の女性の感染発生率と危険因子に関するデータは限られている.
研究 の 目的:
- パルボウイルスB19感染のリスクを特定するために,疫病と流行期間の妊婦.
- この集団におけるパルボウイルスB19感染に関連する危険因子を特定する.
主な方法:
- デンマーク (1992年-1994年) の妊娠女性30,946人を対象とした人口ベースのコホート研究.
- 過去の感染と血清転換を決定するために,特定のIgG抗体に対する血清サンプルを評価する.
- 家族の構造,教育,社会経済的な地位,妊娠の結果に関するデータが収集されました.
主要な成果:
- 妊娠中の女性の65%は,過去にParvovirus B19感染の証拠を示しました.
- 年間血清転換率は1.5% (流行性) と13.0% (流行性) であった.
- 危険因子には,兄弟姉妹の数,同じ年齢の兄弟姉妹,自分の子供,子供への職業的曝露が含まれていました. 幼稚園の教師は,リスクが3倍に増加しました.
結論:
- 感受性の高い妊婦は,感染症の流行の間,感染のリスクが高く,子供との接触レベルと相関しています.
- 幼稚園の教師は職業上のリスクが高くなりますが,ほとんどの感染は女性の子供との接触から発生します.
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