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Updated: Jul 21, 2026

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
10:00

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling

Published on: October 28, 2014

熱ショック - ユビキチン - プロテアソーム経路によるmRNA分解の制御

G Laroia1, R Cuesta, G Brewer

  • 1Department of Microbiology and Biochemistry, New York University School of Medicine, New York, NY 10016, USA.

Science (New York, N.Y.)
|April 16, 1999
PubMed
まとめ

AUに富んだmRNAの分解は,AUF1のタンパク質結合によって調節される. 熱ショックタンパク質70 (hsp70) は,AUF1を隔離し,mRNAの分解を阻害し,それをユビキチン-プロテアソーム経路とリンクします.

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