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脳性不血症イベントを有する患者の心房隔膜動脈瘤の頻度
Y Agmon1, B K Khandheria, I Meissner
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Circulation
|April 20, 1999
まとめ
心房隔膜動脈瘤 (ASA) は,一般人よりも脳性缺血イベントの患者でより一般的です. この発見は,しばしば patent foramen ovale (PFO) と関連付けられているASAが,心臓栓塞の重要な源である可能性があることを示唆しています.
科学分野:
- 心臓病学 心臓病学
- 神経学 神経学とは
- 血管医学 血管医学とは
背景:
- 心房隔膜動脈瘤 (ASA) は,心臓栓塞の潜在的な危険因子です.
- 一般集団におけるASAの罹患率と,脳性缺血イベントとの関連性は,十分に定義されていません.
研究 の 目的:
- 一般集団におけるASAの頻度を決定する.
- ASAの頻度を,脳不全症候群の患者と一般の患者との間で比較する.
主な方法:
- ASAの頻度を決定するために,人口ベースのサンプル (363人の被験者) が使用されました.
- 脳性不全症患者 (355人) のASA発生頻度は,対照群と比較した.
- トランスエゾファゲアルエコーカルディオグラフィーとコントラスト注射を用いた.
主要な成果:
- 一般集団におけるASAの罹患率は2.2%でした.
- ASAは,脳不全症候群の患者の7.9%で発見され,その頻度は著しく高かった (OR,3.65;P=0.002).
- ASAは, patent foramen ovale (PFO) (OR, 4.57) と強く関連していた.
結論:
- 人口ベースのASAの罹患率は2.2%である.
- ASAは,脳性不血症イベントを経験している患者に著しく頻繁に見られます.
- ASAは,しばしばPFOと関連しており,これらの患者における心臓栓塞の原因である可能性が高い.
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