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Updated: Jul 8, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

血管細胞アポトーシス: 細胞の成長因子-β1を内皮細胞と滑らかな筋肉細胞に変換することによって,細胞型特異的な調節

M J Pollman1, L Naumovski, G H Gibbons

  • 1Cardiovascular Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Circulation
|April 20, 1999
PubMed
まとめ

変形成長因子-β1 (TGF-β1) は,血管細胞のアポトーシスを差異的に調節する. TGF-β1は内皮細胞死を促進しますが,細胞-マトリックス相互作用に応じて,血管の滑らかな筋肉細胞のアポプトシスを抑制します.

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Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro08:28

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