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Updated: Aug 2, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

SCFGrr1およびRbx1を含む複合体によるG1サイクリンユビキチネーションの再構成

D Skowyra1, D M Koepp, T Kamura

  • 1Verna and Marrs McLean Department of Biochemistry, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|April 24, 1999
PubMed
まとめ

研究者は細胞サイクル制御をインビトロで再構成し,G1サイクリンCln1がSCF複合体によってどのようにユビキチン化されているかを示した. この研究では,E3ユビキチンリガゼの組立と機能におけるRbx1の役割を明らかにしています.

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Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations

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In Vivo Detection and Analysis of Rb Protein SUMOylation in Human Cells

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