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Updated: Jul 27, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
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フォークヘッド転写因子AFXをタンパク質キナーゼBによって直接制御する

G J Kops1, N D de Ruiter, A M De Vries-Smits

  • 1Laboratory for Physiological Chemistry and Centre for Biomedical Genetics, University of Utrecht, The Netherlands.

Nature
|April 27, 1999
PubMed
まとめ

タンパク質キナーゼBは,フォークヘッド転写因子AFXを調節し,C. elegansのヒトホモログであるDAF-16を調節する. この経路は,核へのPI(3) K依存のシグナル伝達に不可欠です.

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