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米国では,腎臓細胞がんの発生率が上昇しています
W H Chow1, S S Devesa, J L Warren
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7240, USA. choww@exchange.nih.gov
JAMA
|May 11, 1999
まとめ
腎臓がんの発生率は上昇しており,特に腎臓細胞癌 (RCC) が増加しており,初期段階の腫瘍の検出も増加しています. しかし,生存率はすべてのグループで改善されず,死亡率は増加しています.
科学分野:
- 腫瘍学 腫瘍学
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
背景:
- 臨床調査は,偶発的な腎臓細胞癌 (RCC) の検出率の増加を示しています.
- 医療イメージングの手続きの利用が増えることは,この傾向に寄与しています.
研究 の 目的:
- 腎臓細胞がんおよび腎臓骨盤がんの発生率,死亡率,生存率の動向を分析する.
- これらの傾向を,異なる年齢層,性別,人種,診断時の腫瘍の段階などで調べてみてください.
主な方法:
- 国立がん研究所 (National Cancer Institute) のサーベイランス,疫学,および最終結果 (SEER) プログラム (1975-1995) のデータを活用した.
- 年齢調整した発生率と死亡率の計算.
- 腎臓がんの5年相対生存率を決定した.
主要な成果:
- 腎臓細胞癌の発生率は,すべての人種および性別グループで毎年増加し,黒人男性と女性の割合が高くなりました.
- 腎臓盆腔がんの発生率は,白人男性では減少し,他のグループでは安定したままでした.
- 白人の5年生存率は改善したが,黒人の5年生存率は改善しなかった.
結論:
- 画像検査による前症候群性腎臓細胞癌の検出の増加は,発生率の増加を完全に説明するものではありません.
- 他の要因,特に黒人集団の要因は,急激に増加する腎臓細胞癌率についてさらなる調査を必要としています.
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