関連する実験動画
Updated: Jul 16, 2026

06:57
Spinal Cord Transection in the Larval Zebrafish
Published on: May 21, 2014
まとめ
早期のレサス猿の脊髄発達には,重要な細胞の再編成が伴う. 感覚経路は,発達中にニューロンの死と転移を経験します.
科学分野:
- 神経科学は神経科学である.
- 発達生物学 発達生物学とは
- 胚学 胚学について
背景:
- 胚の脊髄は,発達過程で複雑な細胞とシナプスの改造を経験します.
- 神経回路の形成を理解することは,発達神経科学にとって極めて重要です.
研究 の 目的:
- 胚性レサス猿の脊髄における細胞とシナプスの再編成を調査する.
- 感覚象限におけるニューロンとアフェレント接続の発達運命を明らかにする.
主な方法:
- 電子顕微鏡を用いて細胞構造を調べました.
- 細胞の増殖と移動を追跡するために,トリチ化チミジンのオートラジオグラフィを使用した.
主要な成果:
- 後部感覚象限で細胞とシナプス関係の実質的な再配置が観察されました.
- 感覚アファレント軸索からシナプスを受信するニューロン集団の死亡を特定しました.
- 感覚アフェレンツが新たに生成された物質ゼラチノザニューロンに潜在的に移転することを指摘した.
結論:
- レサス猿の早期脊髄発達には,重要なニューロンの改造が特徴である.
- 感覚経路の発達には,プログラムされた細胞死とアファレント経路の再編成が含まれます.
関連する概念動画
The Spinal Cord
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Neurulation
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...
Spinal Cord: Gross Anatomy
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
Spinal Cord: Information Processing
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Somatic Spinal Reflexes
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Spinal Cord
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.

