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関連する概念動画

Cohesion01:07

Cohesion

Cohesion is the attraction between molecules of the same type, such as water molecules. Water molecules have an overall neutral charge but are polar molecule. An oxygen atom in one water molecule has a partial negative charge that can bind to a hydrogen atom with a partial positive charge in a second water molecule, forming a hydrogen bond. Each water molecule can form up to four hydrogen bonds with other water molecules. Hydrogen bonds are responsible for water's cohesive nature.
On a surface,...
Molecules and Compounds02:38

Molecules and Compounds

Atoms and Molecules
Network Covalent Solids02:18

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Globular and Fibrous Proteins02:21

Globular and Fibrous Proteins

Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities.
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...
Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...

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関連する実験動画

Updated: Jul 10, 2026

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
09:27

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles

Published on: August 16, 2012

ポリマーソーム: 二重ブロックコポリマーから作られた頑丈なベジクル.

B M Discher1, Y Y Won, D S Ege

  • 1School of Engineering and Applied Science, and Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|May 15, 1999
PubMed
まとめ

ブロックコポリマーから作られた巨大ポリマーソームは,天然の脂質膜と比較して優越した性および水浸透性が低下しています. これらの合成ベジクルは,薄殻のカプセルという有望な新しいクラスを提供します.

科学分野:

  • マテリアルサイエンス 材料科学
  • バイオフィジックス 生物物理学
  • ポリマー化学のポリマー化学について

背景:

  • 自然の細胞膜は,フォスフォリピドで構成されています.
  • リピド二重層は,生物学的ベジクルとリポソームの基礎を形成する.
  • 脂質二重層に対する合成代替物の理解は,バイオミメティックアプリケーションにとって極めて重要です.

研究 の 目的:

  • アンフィフィリック・ディブロック・コポリマーを用いて,ポリマーベースの水泡 (ポリマーソーム) を合成し,特徴づけること.
  • ポリマーソームの機械的および浸透性特性を天然の脂質膜と比較する.
  • 合成カプセルとしてのポリマーソームの可能性を調査する.

主な方法:

  • アンフィフィリック二重ブロックコポリマー (ポリエチレン酸化物-ポリエチレチレン,EO40-EE37) を用いて膀を形成した.
  • ミクロマニピュレーション技術は,膀の特徴化のために使用されました.
  • 機械的特性 (曲げ方,面積拡大モジュール) と水浸透性が測定されました.

主要な成果:

  • ポリマーソームは,脂質膜に匹敵する膜屈曲と領域拡大モジュールを示した.
  • 巨大ポリマーソームは,破裂前に著しく高い性およびより高い領域張力耐性を示した.

さらに関連する動画

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
11:42

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Published on: June 20, 2019

関連する実験動画

Last Updated: Jul 10, 2026

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
09:27

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles

Published on: August 16, 2012

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
11:42

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Published on: June 20, 2019

  • ポリマーソーム膜は,フォスフォリピド二重層と比較して,水の浸透性が少なくとも10倍減少したことを示しました.

    • 結論:

    • ブロックコポリマーベースのポリマーソームは,堅固な合成ベジケルの新しいクラスを表しています.
    • これらのポリマーソームは,強化された機械的強度と低透性を有し,重要な側面において天然の脂質膜を上回る.
    • ポリマーソームは,高度な合成薄殻カプセルを開発するための有望なプラットフォームを提供します.