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Updated: Jul 21, 2026

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Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
非常に早産で生まれた青少年における脳構造と神経認知機能および行動機能
A L Stewart1, L Rifkin, P N Amess
1Department of Paediatrics, Rayne Institute, University College London Medical School, UK. ann@arlingtonave.demon.co.uk
Lancet (London, England)
|May 21, 1999
まとめ
極めて早産は,思春期における神経認知および行動的問題を増加させる. 磁気共鳴画像 (MRI) は,これらの個体において,以前超音波で検出されたよりも多くの脳の異常を明らかにしました.
科学分野:
- 神経科学は神経科学である.
- 発達小児科 発達小児科
- 放射線学 放射線学
背景:
- 非常に早産 (33週未満) で生まれた乳児は,神経認知機能の欠陥のリスクが高くなります.
- 新生児の超音波検査は8歳までの神経発達の結果を予測しますが,後の機能は理解されていないままです.
- この研究は,非常に早産が青年の脳構造と機能に及ぼす長期的な影響を調査しています.
研究 の 目的:
- 幼児の脳構造に対する非常に早産の影響を調査する.
- 非常に早産児の青少年における神経認知機能と行動機能を評価する.
- 青春期の脳の発見を,人生の初期における要因と結果と相関させる.
主な方法:
- 妊娠33週前に生まれた105人の乳児のコホートを前向きに追跡した.
- 14~15歳のとき,72人の非常に早産した個人と21人の対照群は,脳MRIと神経認知/行動評価を受けた.
- MRIスキャンは,神経放射線科医によって独立してレビューされました.
主要な成果:
- 超早産者の半数以上 (40/72) は,コントロールの1人と比較して,異常なMRIスキャンを受けた.
- 常見のMRI異常は,心室,大 Callosum体,および白質の病変が含まれています.
- 非常に早産した個人は,読書,調整,および神経学的障害が著しく多く,MRIの発見に関連した行動を示しました.
結論:
- 非常に早産した青年は,神経認知および行動障害の有病率が高いことを示しています.
- 超早産児の半数以上は,思春期のMRIで異常な脳構造を示しています.
- MRIは,非常に早産の個体における脳の異常を特定し,長期的な機能に影響を与えるために不可欠です.
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