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Updated: Apr 2, 2026

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RPTP LARのタンデムフォスファタゼドメインの結晶構造

H J Nam1, F Poy, N X Krueger

  • 1Dana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|May 25, 1999
PubMed
まとめ

ヒトのRPTP LARのタンパク質チロシンフォスファタゼ (PTP) D2ドメインの変異により,触媒活性が可能になる. この発見は,PTPase機能とドメイン指向に関する以前のモデルに異議を唱えている.

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