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Isolation and Culture of Pulmonary Endothelial Cells from Neonatal Mice
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エンドグリンが欠けているマウスにおける欠陥性血管新生

D Y Li1, L K Sorensen, B S Brooke

  • 1Program in Human Molecular Biology and Genetics, Department of Human Genetics, Howard Hughes Medical Institute, University of Utah, Salt Lake City, UT 84112-5330, USA. dean.li@hci.utah.edu

Science (New York, N.Y.)
|May 29, 1999
PubMed
まとめ

エンドグリンは血管の発達に不可欠です. エンドグリンが欠けているマウスは,欠陥のある血管性滑らかな筋肉と再構築を示し,胚の致死性につながり,遺伝性出血性テランジエクタシア (HHT1) の原因を示唆します.

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