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BiPは,前プロアルファ因子の翻訳後の輸送中に,ER膜を横切って分子ラッチのように作用します

K E Matlack1, B Misselwitz, K Plath

  • 1Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115-6091, USA.

Cell
|June 15, 1999
PubMed
まとめ

この研究では,タンパク質BiP (Kar2p) が分子ラチェットとして作用し,酵母細胞内プラズマ網膜を横切ってタンパク質の輸送を容易にすることを明らかにしました. このメカニズムは,細胞機能に不可欠な単方向のタンパク質の動きを保証します.

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