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Updated: May 5, 2026

Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells
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Direct Induction of Hemogenic Endothelium and Blood by Overexpression of Transcription Factors in Human Pluripotent Stem Cells

Published on: December 3, 2015

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Pit1とGATA2の相互相互作用は,下垂体細胞のタイプをシグナリンググラデーションによって誘発された決定を媒介する

J S Dasen1, S M O'Connell, S E Flynn

  • 1Howard Hughes Medical Institute, Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla 92093-0648, USA.

Cell
|June 15, 1999
PubMed
まとめ

暫定的なシグナリング・グラデーションは,下垂体細胞の発達を形作る. Pit1とGATA2の転写因子の相互相互作用は分子記憶として作用し,Pit1のDNA結合独立機能は細胞型特異化に不可欠である.

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